In this study, nano silver solution was deoxygenated by using natural cactus powder in the condition of heating , and the diameter and distribution of cactus silver nanoparticles were studied by using HPPS and TEM. After treated by nano silver solution, the antibacterial efficiency and wash durability of the cotton fabric were tested. The results showed that the antibacterial performance of the finished fabric was excellent, even if washed by 30 times.